SEGUL
A cross-platform phylogenomic tool
We develop SEGUL (SEquence and Genomic UtiLities) to address the need for a high-performance and accessible phylogenomic tool. It features a growing list of high-performance, memory-efficient solutions for genomic data exploration, cleaning, filtering, and conversion tasks. We designed SEGUL to handle large-scale phylogenomic datasets involving thousands of loci and hundreds of samples. Additionally, it is capable of handling small Sanger sequences effectively. It scales from smartphones, tablets, and personal computers to high-performance computing clusters. It is available as a command-line app, mobile and desktop GUI, and packages for Rust and Python. Using the SEGUL library in other languages is also possible using the Rust interface, such as in R using extendr. It is a practical solution to typical phylogenomic data analyses and a proof of concept for scalable, cross-platform genomic software. SEGUL received the Society of Systematic Biologists' 2024 Ernst Mayr Award.